" /> Naporafenib - CISMeF





Preferred Label : Naporafenib;

NCIt synonyms : pan-RAF Kinase Inhibitor LXH254; Raf Family Kinase Inhibitor LXH254;

NCIt related terms : pan-RAF Inhibitor LXH254;

NCIt definition : An orally available inhibitor of all members of the serine/threonine protein kinase Raf family, with potential antineoplastic activity. Upon administration, naporafenib binds to Raf proteins and inhibits Raf-mediated signal transduction pathways. This inhibits proliferation of Raf-overexpressing tumor cells. Raf protein kinases are critical enzymes in the Ras/Raf/MEK/ERK signaling pathway and are upregulated in a variety of cancer cell types. They play key roles in tumor cell proliferation and survival.;

UNII : 15JL80DG6H;

InChIKey : UEPXBTCUIIGYCY-UHFFFAOYSA-N;

CAS number : 1800398-38-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1800398-38-2 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : LXH-254; LXH 254;

NCI Metathesaurus CUI : CL503849;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
12/05/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.