proto-oncogene proteins b-raf

Preferred Label : proto-oncogene proteins b-raf;

MeSH definition : A raf kinase subclass found at high levels in neuronal tissue. The B-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.;

MeSH synonym : braf kinases; b-raf, proto-oncogene protein; proteins b-raf, proto-oncogene; proto oncogene protein b raf; b-raf, proto-oncogene proteins; proto-oncogene protein b-raf; protein b-raf, proto-oncogene; b-raf kinases; b raf kinases; proto oncogene proteins B raf; BRAF Kinase; Kinase, BRAF; B-raf Kinase; B raf Kinase; Kinase, B-raf;

CISMeF synonym : EC 2.7.1.37;

Registry Number MeSH : EC 2.7.11.1;

Is substance : O;

UNII : EC 2.7.11.1;

Details

Origin ID

D048493;

UMLS CUI

C0104940;

ATC code(s)
- B-Raf serine-threonine kinase (BRAF) inhibitors [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 [NCIt concept]
- Aurora Kinase C [NCIt concept]
- Cell Division Cycle 7-Related Protein Kinase [NCIt concept]
- Cyclin-Dependent Kinase 10 [NCIt concept]
- Cyclin-Dependent Kinase 2 [NCIt concept]
- Cyclin-Dependent Kinase 3 [NCIt concept]
- Leucine-Rich Repeat Serine/Threonine-Protein Kinase 2 [NCIt concept]
- MAP Kinase-Interacting Serine/Threonine-Protein Kinase 1 [NCIt concept]
- MAP Kinase-Interacting Serine/Threonine-Protein Kinase 2 [NCIt concept]
- Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 Beta [NCIt concept]
- Nik-Related Protein Kinase [NCIt concept]
- Serine/Threonine-Protein Kinase 33 [NCIt concept]
- Serine/Threonine-Protein Kinase B-Raf [NCIt concept]
- Serine/Threonine-Protein Kinase Nek10 [NCIt concept]
- Transcription Initiation Factor TFIID Subunit 1 [NCIt concept]
Indexing information
- 1-(4-(1H-pyrazolo(3,4-d)pyrimidin-4-yloxy)phenyl)-3-(4-chloro-3-(trifluoromethyl)phenyl)urea [MeSH Supplementary Concept]
- 1-(6-(2-(4-(2-dimethylaminoethoxy)phenyl)-5-(pyridin-4-yl)-1H-imidazol-4-yl)benzo(b)thiophen-3-yl)-2,2,2-trifluoroethanol [MeSH Supplementary Concept]
- 2-(3,4,5-trimethoxyphenylamino)-6-(3-acetamidophenyl)pyrazine [MeSH Supplementary Concept]
- 2-(4-chlorobenzylsulfonyl)-3-(4-nitrophenyl)-1-phenylprop-2-en-1-one [MeSH Supplementary Concept]
- 6-(2-(4-(2-dimethylaminoethoxy)phenyl)-5-pyridin-4-yl-3H-imidazol-4-yl)naphthalen-1-ol [MeSH Supplementary Concept]
- 7-(2,6-difluoro-4-(5-methyl-2,5-diazabicyclo(2.2.1)heptan-2-yl)phenyl)-3-(1H-indazol-4-yl)-2-(pyridin-4-yl)pyrazolo(1,5-a)pyrimidine [MeSH Supplementary Concept]
- agerafenib [MeSH Supplementary Concept]
- dabrafenib [MeSH Supplementary Concept]
Record concept(s)
- Proto-Oncogene proteins B-raf [MeSH concept]
Related MeSH Supplementary Concept(s)
- BRAF protein, human [MeSH Supplementary Concept]
- braf protein, mouse [MeSH Supplementary Concept]
- braf protein, rat [MeSH Supplementary Concept]
See also inter- (CISMeF)
- metastatic colorectal cancer with a BRAF V600E mutation [Indication]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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