Leucine-Rich Repeat Serine/Threonine-Protein Kinase 2

Preferred Label : Leucine-Rich Repeat Serine/Threonine-Protein Kinase 2;

NCIt synonyms : EC 2.7.11.1; Dardarin; Leucine-Rich Repeat Serine Threonine-Protein Kinase 2; LRRK2;

NCIt definition : Leucine-rich repeat serine/threonine-protein kinase 2 (2527 aa, 286 kDa) is encoded by the human LRRK2 gene. This protein may play a role in protein phosphorylation.;

Details

Origin ID

C78156;

UMLS CUI

C1531201;

OMIM relation
- Leucine-rich repeat kinase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- LRRK2 protein, human [MeSH Supplementary Concept]
- LRRK2 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- LRRK2 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Leucine-Rich Repeat [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- WD Repeat [NCIt concept]
gene_product_is_element_in_pathway
- Parkinson's Disease Pathway BioCarta [NCIt concept]
gene_product_malfunction_associated_with_disease
- Parkinson Disease [NCIt concept]
gene_product_plays_role_in_biological_process
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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