" /> Tovorafenib - CISMeF





Preferred Label : Tovorafenib;

NCIt synonyms : (R)-2-(1-(6-amino-5-chloropyrimidine-4-carboxamido)ethyl)-N-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide; pan-RAF Kinase Inhibitor DAY101;

NCIt definition : An orally available inhibitor of wild-type and certain mutant forms of A-Raf, B-Raf and C-Raf protein kinases, with potential antineoplastic activity. Upon administration, tovorafenib inhibits Raf-mediated signal transduction pathways, which may lead to an inhibition of tumor cell growth. Raf protein kinases play a key role in the RAF/MEK/ERK signaling pathway, which is often deregulated in human cancers and plays a key role in tumor cell proliferation and survival.;

UNII : ZN90E4027M;

CAS number : 1096708-71-2;

Drug name : Ojemda;

Molecule name : BIIB-024; MLN-2480; TAK-580; DAY 101; DAY-101;

NCI Metathesaurus CUI : CL433881;

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03/07/2025


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