" /> Pan-RAF Inhibitor LY3009120 - CISMeF





Preferred Label : Pan-RAF Inhibitor LY3009120;

NCIt related terms : LY-3009120;

NCIt definition : An orally available inhibitor of all members of the serine/threonine protein kinase Raf family, including A-Raf, B-Raf and C-Raf protein kinases, with potential antineoplastic activity. Upon administration, pan-RAF kinase inhibitor LY3009120 inhibits Raf-mediated signal transduction pathways, which may inhibit tumor cell growth. Raf protein kinases play a key role in the RAF/mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) signaling pathway, which is often dysregulated in human cancers and plays a key role in tumor cell proliferation and survival.;

UNII : 1GDT36RARO;

InChIKey : HHCBMISMPSAZBF-UHFFFAOYSA-N;

CAS number : 1454682-72-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1454682-72-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : DP-4978; LY-3009120;

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Keyword's position in hierarchy(ies) : arborescence

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12/05/2024


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