Serine/Threonine-Protein Kinase 4

Preferred Label : Serine/Threonine-Protein Kinase 4;

NCIt synonyms : Serine/Threonine-Protein Kinase Krs-2; STE20-Like Kinase MST1; EC 2.7.11.1; MST-1; Mammalian STE20-Like Protein Kinase 1; STK4;

NCIt definition : Serine/threonine-protein kinase 4 (487 aa, 56 kDa) is encoded by the human STK4 gene. This protein is involved in the mediation of serine/threonine phosphorylation and hippo signaling.;

Details

Origin ID

C99483;

UMLS CUI

C1448938;

Automatic exact mappings (from CISMeF team)
- Macrophage stimulating 1 [OMIM gene]
- Serine/threonine protein kinase 4 [OMIM gene]
- [tyrosine 3-monooxygenase] kinase activity [GO term]
- macrophage stimulating 1 [ORDO Gene]
- serine/threonine kinase 4 [ORDO Gene]
OMIM relation
- Serine/threonine protein kinase 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- STK4 protein, human [MeSH Supplementary Concept]
- STK4 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- STK4 Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- MAPK Signaling Pathway [NCIt concept]
- Non-Small Cell Lung Cancer Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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