SNCA wt Allele

Preferred Label : SNCA wt Allele;

NCIt synonyms : NACP; MGC110988; PARK4; PARK1; Synuclein, Alpha (Non A4 Component of Amyloid Precursor) wt Allele; PD1; Alpha-Synuclein Gene;

NCIt definition : Human SNCA wild-type allele is located in the vicinity of 4q21 and is approximately 111 kb in length. This allele, which encodes alpha-synuclein protein, is involved in presynaptic signaling and membrane trafficking. Mutation of the gene is associated with Alzheimer disease, Parkinson disease and Lewy body dementia.;

GenBank Accession Number : L08850;

Details

Origin ID

C90113;

UMLS CUI

C2983377;

OMIM relation
- Synuclein, alpha [OMIM gene]
See also inter- (CISMeF)
- parkinson disease 4, autosomal dominant lewy body [MeSH Supplementary Concept]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Alzheimer's Disease [NCIt concept]
- Lewy Body Dementia [NCIt concept]
- Parkinson Disease [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 4q21 [NCIt concept]
gene_is_element_in_pathway
- Alpha-Synuclein Signaling Pathway [NCIt concept]
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- Parkinson's Disease Pathway BioCarta [NCIt concept]
- Parkinson's Disease Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Ligand Binding [NCIt concept]
- Neuronal Transmission [NCIt concept]
- Signal Transduction [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients