" /> Netrin Receptor DCC - CISMeF





Preferred Label : Netrin Receptor DCC;

NCIt synonyms : Deleted in Colorectal Carcinoma Protein; DCC; CRC18; Colorectal Cancer Suppressor; Tumor Suppressor Protein DCC; Immunoglobulin Superfamily DCC Subclass Member 1; DCC Protein; Colorectal Tumor Suppressor;

NCIt definition : Netrin receptor DCC (1447 aa, 158 kDa) is encoded by the human DCC gene. This protein is involved in both axonal guidance and the regulation of apoptosis.;

NCIt note : Netrin receptor DCC is a transmembrane protein of the immunoglobulin superfamily, is expressed on spinal commissural axons and possesses netrin-1-binding activity. Knockout studies in mice failed to support a tumor-suppressor function for DCC in the mouse, but were consistent with the hypothesis that DCC is a component of the receptor for netrin-1, a neuronal chemoattractant. (from OMIM);

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29/07/2025


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