NCIt definition : Human PTK2B wild-type allele is located in the vicinity of 8p21.1 and is approximately
148 kb in length. This allele, which encodes protein tyrosine kinase 2 beta protein,
plays a role in both the calcium-dependent regulation of ion channels and activation
of the map kinase signaling pathway.;
NCIt note : The PTK2B gene undergoes alternative splicing to produce four transcript variants,
although only two protein isoforms have been characterized.;