NEDD8-Activating Enzyme E1 Catalytic Subunit

Preferred Label : NEDD8-Activating Enzyme E1 Catalytic Subunit;

NCIt synonyms : Ubiquitin-Like Modifier-Activating Enzyme 3; NEDD8-Activating Enzyme E1C; Ubiquitin-Activating Enzyme E1C; Ubiquitin-Activating Enzyme 3; EC 6.3.2.-;

NCIt definition : NEDD8-activating enzyme E1 catalytic subunit (463 aa, 52 kDa) is encoded by the human UBA3 gene. This protein is involved in the catalysis of protein neddylation.;

Details

Origin ID

C95858;

UMLS CUI

C1452523;

Automatic exact mappings (from CISMeF team)
- Ubiquitin-like modifier-activating enzyme 3 [OMIM gene]
- ubiquitin like modifier activating enzyme 3 [HGNC gene]
OMIM relation
- Ubiquitin-like modifier-activating enzyme 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- NAE protein, human [MeSH concept]
- NAE protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Ligase Gene [NCIt concept]
- UBA3 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Coregulation Pathway for Androgen Receptor Activity [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
gene_product_is_physical_part_of
- NEDD8 Activating Enzyme [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cell Cycle Checkpoint [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]

Keyword's position in hierarchy(ies) :

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