" /> KLLN wt Allele - CISMeF





Preferred Label : KLLN wt Allele;

NCIt synonyms : Killin Protein Gene; KLN; CWS4; KILLIN; Killin, p53-Regulated DNA Replication Inhibitor Gene; Killin, p53 Regulated DNA Replication Inhibitor wt Allele;

NCIt definition : Human KLLN wild-type allele is located in the vicinity of 10q23 and is approximately 4 kb in length. This allele, which encodes killin protein, plays a role in both DNA binding and the mediation of p53-mediated apoptosis.;

NCIt note : Methylation of the KILLIN gene promoter may be associated with Cowden syndrome, Cowden-like syndrome and cancer susceptibility. (JAMA. 2010; 304:2724-2731.); The human KILLIN gene shares promoter sequences with the human PTEN gene. (OMIM);

GenBank Accession Number : EU552092;

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31/07/2025


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