Chymotrypsinogen B

Preferred Label : Chymotrypsinogen B;

NCIt synonyms : EC 3.4.21.1; Chymotrypsinogen B1; CTRB1;

NCIt definition : Chymotrypsinogen B (263 aa, 28 kDa) is encoded by the human CTRB1 gene. This protein plays a role in proteolytic processes during digestion of nutrients.;

NCIt note : Chymotrypsinogen B is rapidly cleaved at two sites by trypsin to release the active form, chymotrypsin B chain C.;

Details

Origin ID

C118243;

UMLS CUI

C2606397;

Automatic exact mappings (from CISMeF team)
- Chymotrypsinogen b1 [OMIM gene]
- chymotrypsinogen B1 [HGNC gene]
OMIM relation
- Chymotrypsinogen b1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CTRB1 protein, human [MeSH concept]
gene_encodes_gene_product
- CTRB1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Digestive System [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Digestion [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Degradation Induction [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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