Trypsin-2 - CISMeF

Preferred Label : Trypsin-2;

NCIt synonyms : Trypsin 2; Trypsinogen 2; Protease Serine 2 Preproprotein; Anionic Trypsinogen; EC 3.4.21.4; Trypsin II; Serine Protease 2; PRSS2;

NCIt definition : Trypsin-2 (247 aa, 26 kDa) is encoded by the human PRSS2 gene. This protein is involved in the catabolism of proteins in the small intestine.;

NCIt note : Trypsin-2 proteolyzes linkages involving the carboxyl group of lysine or arginine. (EntrezGene);

Details

Origin ID

C118562;

UMLS CUI

C0103396;

Automatic exact mappings (from CISMeF team)
- Protease, serine, 2 [OMIM gene]
- serine protease 2 [ORDO Gene]
- serine protease 2 [HGNC gene]
OMIM relation
- Protease, serine, 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PRSS2 protein, human [MeSH Supplementary Concept]
- PRSS2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PRSS2 Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Ileum [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Digestion [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Degradation Induction [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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