Serine/Threonine-Protein Kinase PINK1, Mitochondrial

Preferred Label : Serine/Threonine-Protein Kinase PINK1, Mitochondrial;

NCIt synonyms : PTEN-Induced Putative Kinase Protein 1; EC 2.7.11.1; PTEN Induced Kinase 1; PINK1; PTEN-Induced Kinase 1; BRPK;

NCIt definition : Serine/threonine-protein kinase PINK1, mitochondrial (581 aa, 63 kDa) is encoded by the human PINK1 gene. This protein is involved in serine/threonine phosphorylation of mitochondrial quality control proteins.;

Details

Origin ID

C204492;

UMLS CUI

C1570961;

OMIM relation
- Pten-induced kinase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PINK1 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- PINK1 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Inner Mitochondrial Membrane [NCIt concept]
- Outer Mitochondrial Membrane [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Amyotrophic Lateral Sclerosis Pathway [NCIt concept]
- Parkinson's Disease Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Phosphorylation Process [NCIt concept]
- Protein Degradation Induction [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Stress Response Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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