NCIt definition : Human HSF1 wild-type allele is located in the vicinity of 8q24.3 and is approximately
23 kb in length. This allele, which encodes heat shock factor protein 1, is involved
in the transcriptional regulation of genes that are involved in the cellular response
to thermal stress.;
NCIt note : Recent studies have shown decreased carcinogenesis in mice that are deficient for
the HSF1 gene. (Cell 2007;130:1005-18.);