Peroxisome Biogenesis Factor 10

Preferred Label : Peroxisome Biogenesis Factor 10;

NCIt synonyms : Peroxisome Assembly Protein 10; Peroxin 10; EC 2.3.2.27; Peroxin-10; PEX10; RING Finger Protein 69;

NCIt definition : Peroxisome biogenesis factor 10 (326 aa, 37 kDa) is encoded by the human PEX10 gene. This protein is involved in both polyubiquitination of peroxisomal targeting signal 1 receptor (PEX5) and export of PEX5 from the proteosome.;

NCIt note : The peroxisome retrotranslocation channel is comprised of peroxisome biogenesis factor proteins 2, 10 and 12. (UniProt);

Détails

Origin ID

C204215;

UMLS CUI

C1449205;

OMIM relation
- Peroxisome biogenesis factor 10 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- PEX10 protein, human [MeSH Supplementary Concept]
- PEX10 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- PEX10 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Membrane of the Peroxisome [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Ring Finger Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Peroxisome Biogenesis Pathway [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- Cellular Stress Response [NCIt concept]
- Ligand Binding [NCIt concept]
- Polyubiquitination [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transport Process [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]
- Unfolded Protein Response [NCIt concept]

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