Heat Shock Protein Beta-1

Preferred Label : Heat Shock Protein Beta-1;

NCIt synonyms : Heat Shock Protein 27; Stress-responsive Protein 27; 28 kDa Heat Shock Protein; HSP 27; Estrogen-regulated 24 kDa Protein; HSPB1; SRP27; Hsp27; Heat Shock 27 kDa Protein; Heat Shock 27kD Protein-1;

NCIt definition : Heat shock protein beta-1 (205 aa, 23 kDa) is encoded by the human HSPB1 gene. This protein is involved in protein denaturation and the cellular response to oxidative stress.;

Details

Origin ID

C16671;

UMLS CUI

C1447061;

OMIM relation
- Heat-shock 27-kd protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- HSPB1 protein, human [MeSH concept]
- HSPB1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Chaperone Protein Gene [NCIt concept]
- HSPB1 Gene [NCIt concept]
gene_product_has_biochemical_function
- Regulatory Protein [NCIt concept]
- Small Heat Shock Protein [NCIt concept]
- Stress-Induced Protein [NCIt concept]
gene_product_is_element_in_pathway
- Amoebiasis Pathway [NCIt concept]
- HSP27 Regulation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MTA3 Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- VEGFR1 and VEGFR2 Signaling [NCIt concept]
- p38 MAPK Signaling Pathway BioCarta [NCIt concept]
- p38 MAPK/MAPKAP Signaling Pathway [NCIt concept]
- p38-alpha and p38-beta Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Survival [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Heat-Shock Response [NCIt concept]
- Protein Folding [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
is_target
- Apatorsen [NCIt concept]

Keyword's position in hierarchy(ies) :

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