Heat Shock 70 kDa Protein 1A/1B

Preferred Label : Heat Shock 70 kDa Protein 1A/1B;

NCIt synonyms : DnaK-Type Molecular Chaperone HSP70-1; HSPA1; HSP70-1/HSP70-2; HSP72; HSP70.1/HSP70.2; Heat Shock 70 kDa Protein 1/2; Heat Shock 70 kDa Protein 1; HSPA1A/HSPA1B;

NCIt definition : Heat shock 70 kDa protein 1A/1B (641 aa, 70 kDa) is encoded by the human HSPA1A and HSPA1B genes. This protein is involved in the mediation of protein folding.;

Details

Origin ID

C104001;

UMLS CUI

C3537327;

OMIM relation
- Heat-shock 70-kd protein 1a [OMIM gene]
- Heat-shock 70-kd protein 1b [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Chaperone Protein Gene [NCIt concept]
- HSPA1A Gene [NCIt concept]
- HSPA1B Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Endoplasmic Reticulum [NCIt concept]
gene_product_has_biochemical_function
- Heat Shock Protein 70 [NCIt concept]
- Regulatory Protein [NCIt concept]
gene_product_is_element_in_pathway
- Antigen Processing and Presentation Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- FOXM1 Transcription Factor Signaling Pathway [NCIt concept]
- Hypoxia Pathway [NCIt concept]
- Interferon Signaling Modulation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- PPAR-alpha Gene Regulation Pathway [NCIt concept]
- Prion Disease Pathway [NCIt concept]
- Spliceosome Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Growth Regulation [NCIt concept]
- Heat-Shock Response [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Protein Folding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Unfolded Protein Response [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients