HSPA1A wt Allele

Preferred Label : HSPA1A wt Allele;

NCIt synonyms : HSP70I; HSP70-1A; HSP70-1; Heat Shock 70 kDa Protein 1A wt Allele; HSP72; DAQB-147D11.1; HSPA1;

NCIt definition : Human HSPA1A wild-type allele is located in the vicinity of 6p21.3 and is approximately 2 kb in length. This allele, which encodes heat shock 70 kDa protein 1A/1B, plays a role in protein chaperone activity.;

NCIt note : The coding sequences of HSPA1A and HSPA1B differ by 8 base pairs but encode identical proteins. However, the 3-prime untranslated regions of these genes are completely divergent. (OMIM);

GenBank Accession Number : BC002453;

Details

Origin ID

C103999;

UMLS CUI

C3541976;

OMIM relation
- Heat-shock 70-kd protein 1a [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 6p21.3 [NCIt concept]
gene_is_element_in_pathway
- Antigen Processing and Presentation Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- FOXM1 Transcription Factor Signaling Pathway [NCIt concept]
- Hypoxia Pathway [NCIt concept]
- Interferon Signaling Modulation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- PPAR-alpha Gene Regulation Pathway [NCIt concept]
- Prion Disease Pathway [NCIt concept]
- Spliceosome Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Growth Regulation [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Protein Folding [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Unfolded Protein Response [NCIt concept]

Keyword's position in hierarchy(ies) :

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