Heat Shock Protein Beta-8

Preferred Label : Heat Shock Protein Beta-8;

NCIt synonyms : E2-Induced Gene 1 Protein; Small Stress Protein-Like Protein HSP22; HspB8; Alpha-Crystallin C Chain; Protein Kinase H11;

NCIt definition : Heat shock protein beta-8 (196 aa, 22 kDa) is encoded by the human HSPB8 gene. This protein plays a role in the regulation of autophagy and as a protein chaperone.;

NCIt note : Heat shock protein beta-8 may have serine/threonine protein kinase activity. (J. Biol. Chem. 2000; 275: 25690-25699.);

Details

Origin ID

C95435;

UMLS CUI

C2987147;

OMIM relation
- Heat-shock 22-kd protein 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- Chaperone Protein Gene [NCIt concept]
- HSPB8 Gene [NCIt concept]
gene_product_has_biochemical_function
- Chaperone [NCIt concept]
- Regulatory Protein [NCIt concept]
- Small Heat Shock Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- Autophagy [NCIt concept]
- Heat-Shock Response [NCIt concept]
- Protein Folding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Unfolded Protein Response [NCIt concept]

Keyword's position in hierarchy(ies) :

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