Peroxisome Assembly Protein 12

Preferred Label : Peroxisome Assembly Protein 12;

NCIt synonyms : Peroxisome Assembly Factor 3; Peroxin 12; Peroxisomal Biogenesis Factor 12; Peroxisome Biogenesis Factor 12; PAF-3; Peroxin-12; PEX12;

NCIt definition : Peroxisome assembly protein 12 (359 aa, 41 kDa) is encoded by the human PEX12 gene. This protein plays a role in the export of peroxisomal targeting signal 1 receptor (PEX5) from the peroxisome to the cytoplasm.;

NCIt note : The peroxisome retrotranslocation channel is comprised of peroxisome biogenesis factor proteins 2, 10 and 12. (UniProt);

Details

Origin ID

C204218;

UMLS CUI

C1449054;

OMIM relation
- Peroxisome biogenesis factor 12 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PEX12 protein, human [MeSH Supplementary Concept]
- PEX12 protein, human [MeSH concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- PEX12 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Membrane of the Peroxisome [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Ring Finger Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Peroxisome Biogenesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cellular Stress Response [NCIt concept]
- Ligand Binding [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transport Process [NCIt concept]
- Ubiquitination [NCIt concept]
- Unfolded Protein Response [NCIt concept]

Keyword's position in hierarchy(ies) :

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