CUL1 wt Allele

Preferred Label : CUL1 wt Allele;

NCIt synonyms : Cullin 1 wt Allele;

NCIt definition : Human CUL1 wild-type allele is located in the vicinity of 7q36.1 and is approximately 102 kb in length. This allele, which encodes cullin-1 protein, plays a role in regulating the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription.;

NCIt note : The CUL1 gene is a candidate tumor suppressor gene.;

GenBank Accession Number : NM_003592;

Details

Origin ID

C52062;

UMLS CUI

C1707165;

OMIM relation
- Cullin 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 7: 147833581-147935850 [NCIt concept]
gene_in_chromosomal_location
- 7q36.1 [NCIt concept]
gene_is_element_in_pathway
- Canonical Wnt Signaling Pathway [NCIt concept]
- Cell Cycle Pathway [NCIt concept]
- Circadian Rhythm Pathway KEGG [NCIt concept]
- Cyclin E Degradation Pathway [NCIt concept]
- E2F1 Degradation Pathway [NCIt concept]
- Endoplasmic Reticulum Degradation Pathway [NCIt concept]
- Oocyte Meiosis Pathway [NCIt concept]
- TGF-beta Signaling Pathway KEGG [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
- p27 Regulation Pathway [NCIt concept]
gene_plays_role_in_process
- Protein Degradation Process [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients