Cullin Family Protein

Preferred Label : Cullin Family Protein;

NCIt definition : A protein family whose members are components of ubiquitin ligase complexes, which are involved in ubiquitination and proteasomal degradation of target proteins. Cullins may act as a scaffold to promote the association of substrates with ubiquitin-conjugating enzymes.;

Details

Origin ID

C26091;

UMLS CUI

C1333168;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Cullin Family Gene [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- Protein Degradation Process [NCIt concept]
- Ubiquitination [NCIt concept]
is_chemical_classification_of_gene_product
- Cullin-1 [NCIt concept]
- Cullin-2 [NCIt concept]
- Cullin-3 [NCIt concept]
- Cullin-4A [NCIt concept]
- Cullin-4B [NCIt concept]
- Cullin-5 [NCIt concept]

Keyword's position in hierarchy(ies) :

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