Cullin-2 - CISMeF

Preferred Label : Cullin-2;

NCIt synonyms : Cullin 2 Protein; CUL-2; Cullin 2; CUL2; Cullin Homolog 2; Cullin-2 Protein;

NCIt definition : Cullin-2 (745 aa, 87 kDa) is encoded by the human CUL2 gene. This protein is involved in both cell cycle regulation and protein ubiquitination.;

Details

Origin ID

C26090;

UMLS CUI

C1333165;

OMIM relation
- Cullin 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- CUL2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_biochemical_function
- Scaffolding Protein [NCIt concept]
gene_product_has_chemical_classification
- Cullin Family Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Hypoxia and Oxygen Homeostasis Regulation of HIF-1-Alpha Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
gene_product_is_physical_part_of
- E3 Ubiquitin-Protein Transferase [NCIt concept]
gene_product_plays_role_in_biological_process
- Protein Degradation Process [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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