ATP-Dependent Clp Protease Proteolytic Subunit, Mitochondrial

Preferred Label : ATP-Dependent Clp Protease Proteolytic Subunit, Mitochondrial;

NCIt synonyms : EC 3.4.21.92; Endopeptidase Clp; Caseinolytic Mitochondrial Matrix Peptidase Proteolytic Subunit; CLPP;

NCIt definition : ATP-dependent Clp protease proteolytic subunit, mitochondrial (277 aa, 30 kDa) is encoded by the human CLPP gene. This protein is involved in ATP-dependent degradation of misfolded or unfolded proteins.;

Details

Origin ID

C183178;

UMLS CUI

C3253014;

Automatic exact mappings (from CISMeF team)
- Caseinolytic mitochondrial matrix peptidase proteolytic subunit [OMIM gene]
- Endopeptidase Clp (substance) [SNOMED CT concept]
- caseinolytic mitochondrial matrix peptidase proteolytic subunit [HGNC gene]
- caseinolytic mitochondrial matrix peptidase proteolytic subunit [ORDO Gene]
- endopeptidase clp [MeSH Descriptor]
- endopeptidase clp [MeSH concept]
OMIM relation
- Caseinolytic mitochondrial matrix peptidase proteolytic subunit [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ClpP protein, human [MeSH Supplementary Concept]
- ClpP protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CLPP Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Hepatic Tissue [NCIt concept]
- Skeletal Muscle Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrial Matrix [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Catabolic Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Degradation Process [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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