" /> Pancreatic Elastase - CISMeF





Preferred Label : Pancreatic Elastase;

NCIt synonyms : CELA Family; CELA; Chymotrypsin-Like Elastase; Chymotrypsin-Like Elastase Family;

NCIt definition : A family of chymotrypsin-like serine proteinases that specifically hydrolyze amino bonds on the carboxyl side of hydrophobic amino acids, including alanine, leucine, methionine and phenylalanine. These enzymes play roles in digestion and pancreatic regulation of insulin. Elastin is a substrate for some members of the family. Measurement of the concentration of certain pancreatic elastase isoforms in feces can be correlated to the exocrine secretory capacity of the pancreas.;

NCIt note : Humans express five pancreatic elastases: CELA1, CELA2A, CELA2B, CELA3A and CELA3B. CELA1 is not expressed by the pancreas.;

NCI Metathesaurus CUI : CL1905122;

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30/07/2025


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