pancreatic elastase

Preferred Label : pancreatic elastase;

MeSH definition : A protease of broad specificity, obtained from dried pancreas. Molecular weight is approximately 25,000. The enzyme breaks down elastin, the specific protein of elastic fibers, and digests other proteins such as fibrin, hemoglobin, and albumin. EC 3.4.21.36.;

MeSH synonym : elastase i, pancreatic; elastase, pancreatic; pancreatic elastase i; elastase; pancreatopeptidase;

MeSH hyponym : elastase I;

Registry Number MeSH : EC 3.4.21.36;

MeSH annotation : LEUKOCYTE ELASTASE is also available;

Is substance : O;

UNII : EC 3.4.21.36;

Details

Origin ID

D010196;

UMLS CUI

C0030306;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Chymotrypsin-like elastase family, member 1 [OMIM gene]
- Elastase [ICHI extension code]
CISMeF manual mappings
- Substance with elastase inhibitor mechanism of action (substance) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Elastase.pancreatic [LOINC component]
- Pancreatic Elastase [NCIt concept]
- Pancreatic elastase (substance) [SNOMED CT concept]
- pancreatic elastase [SNOMED Notion]
Indexing information
- (1-(5-methyl-4-oxo-4H-3,1-benzoxazin-2-yl)-2-methylpropyl)carbamic acid 1,1-dimethylethyl ester [MeSH Supplementary Concept]
- 2-(4-fluorophenyl)-5-((methoxycarbonyl)amino)pyrimidin-4-one-3-ethanoylvaline-trifluoromethylketone [MeSH Supplementary Concept]
- 2-mercaptoacetyl-phenylalanylleucine [MeSH Supplementary Concept]
- 3-acetoxymethyl-7-chloro-3-cephem-4-carboxylate-1,1-dioxide tert-butylester [MeSH Supplementary Concept]
- 3-benzyl-N-(methanesulfonyloxy)succinimide [MeSH Supplementary Concept]
- 4-hydroxy-6-((1-butyl)heptyl)-2H-pyran-2-one [MeSH Supplementary Concept]
- 4-hydroxy-6-undecyl-2H-pyran-2-one [MeSH Supplementary Concept]
- 4-methoxy-6-((1-butyl)heptyl)-2H-pyran-2-one [MeSH Supplementary Concept]
- 4-nitrophenyl [MeSH Supplementary Concept]
- 4-nitrophenyl N-(succinyl-alanyl-alanyl-prolylmethyl)-N-isopropylcarbamate [MeSH Supplementary Concept]
- 7-((N-tosylphenylalanyl)amino)-4-chloro-3-methoxyisocoumarin [MeSH Supplementary Concept]
- ASPI-2 protein, ascaris suum [MeSH Supplementary Concept]
- CDSO3 compound [MeSH Supplementary Concept]
- CEI protein, trichuris suis [MeSH Supplementary Concept]
- DMP 777 [MeSH Supplementary Concept]
- FK 706 [MeSH Supplementary Concept]
- FR 901451 [MeSH Supplementary Concept]
- ICI 200355 [MeSH Supplementary Concept]
- L 658758 [MeSH Supplementary Concept]
- L 680833 [MeSH Supplementary Concept]
- L 708286 [MeSH Supplementary Concept]
- MDL 101146 [MeSH Supplementary Concept]
- MDL 27324 [MeSH Supplementary Concept]
- MDL 27399 [MeSH Supplementary Concept]
- N(alpha)-(1-adamantanesulfonyl)-N(epsilon)-(4-carboxybenzoyl)lysyl-alanyl-valinal [MeSH Supplementary Concept]
- N-((4-((((4-chlorophenyl)sulfonyl)amino)carbonyl)phenyl)oxomethyl)-valyl-N-(2,3-dihydro-1H-inden-2-yl)glycine N-(3-(1,1,1-trifluoro-4-methyl-2-oxopentyl))amide [MeSH Supplementary Concept]
- N-(2-chloromethylphenyl)-3,3-difluoroazetidin-2-one [MeSH Supplementary Concept]
- N-(tert-butoxycarbonyl)alanyl-alanyl-O'-(2,3-epoxypropyl)tyrosine ethyl ester [MeSH Supplementary Concept]
- N-(trifluoroacetyl)valyl-O'-(2,3-epoxypropyl)tyrosyl-valine methyl ester [MeSH Supplementary Concept]
- N-phenethylphosphonyl-leucyl-tryptophan [MeSH Supplementary Concept]
- N-phenetylphosphonyl-leucyl-tryptophane [MeSH Supplementary Concept]
- PVI-3(1) protein, phaseolus vulgaris [MeSH Supplementary Concept]
- SC 37698 [MeSH Supplementary Concept]
- SR 26831 [MeSH Supplementary Concept]
- SSR 69071 [MeSH Supplementary Concept]
- TEI 5624 [MeSH Supplementary Concept]
- TEI 6344 [MeSH Supplementary Concept]
- acetylalanyl-prolyl-valyl-trifluoromethyl ketone [MeSH Supplementary Concept]
- chloroacetyl-N-hydroxyleucyl-alanyl-glycinamide [MeSH Supplementary Concept]
- elastatinal [MeSH Supplementary Concept]
- glutaryl-alanyl-alanyl-alanyl-ethylamide [MeSH Supplementary Concept]
- glutaryl-alanyl-alanyl-alanyl-propylamide [MeSH Supplementary Concept]
- glutaryl-alanyl-alanyl-prolylethylamide [MeSH Supplementary Concept]
- lobechine [MeSH Supplementary Concept]
- lodelaben [MeSH Supplementary Concept]
- lyngbyastatin 10 [MeSH Supplementary Concept]
- lyngbyastatin 8 [MeSH Supplementary Concept]
- lyngbyastatin 9 [MeSH Supplementary Concept]
- methoxysuccinate-alanyl-alanyl-valine chloromethyl ketone [MeSH Supplementary Concept]
- methoxysuccinyl-alanyl-alanyl-prolyl-alanine chloromethyl ketone [MeSH Supplementary Concept]
- methoxysuccinyl-alanyl-alanyl-prolyl-valine chloromethyl ketone [MeSH Supplementary Concept]
- methyl-O-succinyl-alanyl-alanyl-prolyl-borovaline-pinacol [MeSH Supplementary Concept]
- methyl-O-succinyl-alanyl-alanyl-prolyl-borovaline-pinacol [MeSH Supplementary Concept]
- microviridin B [MeSH Supplementary Concept]
- ovomucoid inhibitors [MeSH Supplementary Concept]
- protease inhibitor protein, tylosema esculenturm [MeSH Supplementary Concept]
- pseudolysin, pseudomonas aeruginosa [MeSH Supplementary Concept]
- succinyl-alanyl-alanyl-prolyl-valine chloromethyl ketone [MeSH Supplementary Concept]
- tert-butoxycarbonyl-tyrosyl-leucyl-valyl-chloromethane [MeSH Supplementary Concept]
- tetrapeptide carbamate [MeSH Supplementary Concept]
- trifluoroacetyl-dialanine-4-nitroanilide [MeSH Supplementary Concept]
- trifluoroacetyl-leucyl-alanyl-4-trifluoromethylanilide [MeSH Supplementary Concept]
- trifluoroacetyl-lysyl-alaninanilide [MeSH Supplementary Concept]
- trifluoroacetyllysylalanine-trifluoromethylphenylanilide [MeSH Supplementary Concept]
- trifluoroacetylphenylalanylalanine 4-trifluoromethylanilide [MeSH Supplementary Concept]
- trifluoroacetylvalylalanine 4-trifluoromethylanilide [MeSH Supplementary Concept]
- undecenoyl-aspartyl-dialanyl-proline ethylamide [MeSH Supplementary Concept]
Record concept(s)
- elastase I [MeSH concept]
- pancreatic elastase [MeSH concept]
Related MeSH Supplementary Concept(s)
- CELA1 protein, human [MeSH Supplementary Concept]
- CELA1 protein, mouse [MeSH Supplementary Concept]
- CELA3A protein, human [MeSH Supplementary Concept]
- CELA3B protein, human [MeSH Supplementary Concept]
- ahyB protein, aeromonas hydrophila [MeSH Supplementary Concept]
- alkaline elastase [MeSH Supplementary Concept]
- anhydroelastase [MeSH Supplementary Concept]
- cholesterol-binding protein [MeSH Supplementary Concept]
- ela3l protein, zebrafish [MeSH Supplementary Concept]
- elastase A, zebrafish [MeSH Supplementary Concept]
- myxococcus xanthus alkaline protease 1 [MeSH Supplementary Concept]
- preproelastases [MeSH Supplementary Concept]
- proelastase [MeSH Supplementary Concept]
- rubelase, crotalus ruber ruber [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Elastase [LOINC component]
- Elastase.pancreatic [LOINC component]
- Pancreatic Elastase [NCIt concept]
- Pancreatic elastase (substance) [SNOMED CT concept]
- pancreatic elastase [SNOMED Notion]
Validated automatic mappings to NTBT
- Elastase [ICD-11 Extension code]
- Elastase [LOINC component]

Keyword's position in hierarchy(ies) :

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