CUL5 wt Allele

Preferred Label : CUL5 wt Allele;

NCIt synonyms : Cullin 5 wt Allele; VACM1; VACM-1;

NCIt definition : Human CUL5 wild-type allele is located within 11q22-q23 and is approximately 98 kb in length. This allele, which encodes cullin-5 protein, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins.;

NCIt note : The CUL5 gene is putatively involved in the proteasome-mediated degradation of the TP53 protein, a process stimulated by the adenovirus E1B-55 kDa protein.;

GenBank Accession Number : NM_003478;

Details

Origin ID

C52066;

UMLS CUI

C1705705;

OMIM relation
- Cullin 5 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 11: 107384855-107482789 [NCIt concept]
gene_in_chromosomal_location
- 11q22-q23 [NCIt concept]
gene_is_element_in_pathway
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
gene_plays_role_in_process
- Protein Degradation Process [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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