CUL3 wt Allele

Preferred Label : CUL3 wt Allele;

NCIt synonyms : Cullin 3 wt Allele; KIAA0617; PHA2E;

NCIt definition : Human CUL3 wild-type allele is located in the vicinity of 2q36.2 and is approximately 115 kb in length. This allele, which encodes cullin-3 protein, plays a role in regulation of the G1/S transition of the cell cycle via the ubiquitination of certain cyclin proteins.;

GenBank Accession Number : NM_003590;

Details

Origin ID

C52064;

UMLS CUI

C1705985;

Automatic exact mappings (from CISMeF team)
- Pseudohypoaldosteronism type 2E [ORDO Disease]
- Pseudohypoaldosteronism, type iie [OMIM Phenotype]
OMIM relation
- Cullin 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 2: 225275619-225160374 [NCIt concept]
gene_in_chromosomal_location
- 2q36.3 [NCIt concept]
gene_is_element_in_pathway
- ATF-2 Transcription Factor Signaling Pathway [NCIt concept]
- Aurora B Signaling Pathway [NCIt concept]
- Canonical Wnt Signaling Pathway [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
gene_plays_role_in_process
- Protein Degradation Process [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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