Elongin-C - CISMeF

Preferred Label : Elongin-C;

NCIt synonyms : EloC; RNA Polymerase II Transcription Factor SIII Subunit C; Transcription Elongation Factor B Subunit 1; Transcription Elongation Factor B Polypeptide 1; Elongin C; Elongin 15 kDa Subunit; SIII p15;

NCIt definition : Elongin-C (112 aa, 12 kDa) is encoded by the human ELOC gene. This protein plays a role in the positive regulation of transcriptional elongation.;

NCIt note : A complex comprised of elongins B and C may regulate ubiquitin-mediated protein degradation. (UniProt); The elongin (SIII) complex is comprised of a heterotrimer of with A (ELOA, ELOA2 or ELOA3), B (ELOB) and C (ELOC) subunits, formerly transcription elongation factor B (TCEB) polypeptides 3, 2 and 1, respectively. (UniProt);

Details

Origin ID

C115423;

UMLS CUI

C1612054;

Automatic exact mappings (from CISMeF team)
- Elongin C [OMIM gene]
- elongin C [MeSH concept]
- elongin C [HGNC gene]
OMIM relation
- Elongin C [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ELOC protein, human [MeSH Supplementary Concept]
- ELOC protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ELOC Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
- Nucleoplasm [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_chemical_classification
- Protein Complex Subunit [NCIt concept]
gene_product_is_element_in_pathway
- HIF-2-Alpha Transcription Factor Pathway [NCIt concept]
- Hypoxia and Oxygen Homeostasis Regulation of HIF-1-Alpha Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
gene_product_is_physical_part_of
- Elongin [NCIt concept]
gene_product_plays_role_in_biological_process
- Protein Degradation Process [NCIt concept]
- Transcription Elongation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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