NCIt synonyms : Matrix Metalloproteinase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa type IV Collagenase)
wt Allele; CLG4B; GELB;
NCIt definition : Human MMP9 wild-type allele is located within 20q11.2-q13.1 and is approximately 8
kb in length. This allele, which encodes matrix metalloproteinase-9 protein, plays
a role in the breakdown of the extracellular matrix via the degradation of both gelatins
(types I and V) and interstitial collagens (types IV and V). The MMP9 gene is associated
with neoplasm invasiveness.;