KLK6 wt Allele

Preferred Label : KLK6 wt Allele;

NCIt synonyms : Klk7; Bssp; Kallikrein Related Peptidase 6 wt Allele; Protease, Serine, 18 Gene; hK6; PRSS9; Protease, Serine, 9 Gene; SP59; Kallikrein 6 (Neurosin, Zyme) Gene; PRSS18;

NCIt definition : Human KLK6 wild-type allele is located in the vicinity of 19q13.41 and is approximately 11 kb in length. This allele, which encodes kallikrein-6 protein, plays a role in post-translational protein processing.;

NCIt note : Germline single nucleotide polymorphisms in the KLK6 region may be associtated with an increased predisposition for aggressive prostate cancer. (J Natl Cancer Inst. 2017; 109: djw258. doi.10.1093/jnci/djw258.);

NCI Metathesaurus CUI : CL521802;

GenBank Accession Number : U62801;

Details

Origin ID

C133890;

UMLS CUI

C4521372;

Automatic exact mappings (from CISMeF team)
- Kallikrein-related peptidase 6 [OMIM gene]
- Kallikrein-related peptidase 7 [OMIM gene]
- serine endopeptidases [MeSH Descriptor]
- serine proteases [MeSH Descriptor]
OMIM relation
- Kallikrein-related peptidase 6 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 19q13.41 [NCIt concept]
gene_is_element_in_pathway
- Alpha-Synuclein Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Hydrolysis [NCIt concept]
- Protein Degradation Process [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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