GZMB wt Allele

Preferred Label : GZMB wt Allele;

NCIt synonyms : CCPI; CGL1; CSPB; Granzyme B (Granzyme 2, Cytotoxic T-Lymphocyte-Associated Serine Esterase 1) wt Allele; CTLA1; GRB; CSP-B; SECT; CGL-1; HLP; CTSGL1; Protease, Serine, B Gene;

NCIt related terms : GranzB;

NCIt definition : Human GZMB wild-type allele is located in the vicinity of 14q11.2 and is approximately 3 kb in length. This allele, which encodes granzyme B protein, is involved in both proteolysis and cellular immune responses.;

GenBank Accession Number : BC030195;

Details

Origin ID

C104354;

UMLS CUI

C3538708;

OMIM relation
- Granzyme b [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 14q11.2 [NCIt concept]
gene_is_element_in_pathway
- Allograft Rejection Pathway [NCIt concept]
- Apoptotic DNA Fragmentation Pathway [NCIt concept]
- Autoimmune Thyroid Disease Pathway [NCIt concept]
- Caspase Cascade Pathway [NCIt concept]
- Caspase Cascade in Apoptosis [NCIt concept]
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Graft-Versus-Host Disease Pathway [NCIt concept]
- Granzyme A Mediated Apoptosis Pathway [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Type I Diabetes Mellitus Pathway [NCIt concept]
gene_plays_role_in_process
- Cell-Mediated Cytotoxicity [NCIt concept]
- Hydrolysis [NCIt concept]
- Positive Regulation of Cytolytic Process [NCIt concept]
- Protein Cleavage [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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