Granzyme A - CISMeF

Preferred Label : Granzyme A;

NCIt synonyms : Hanukah Factor Serine Protease; Granzyme-1; Cytotoxic T-Lymphocyte-Associated Serine Esterase 3; CTL Tryptase; Fragmentin-1; EC 3.4.21.78; HF; H Factor; Hanukkah Factor; Cytotoxic T-Lymphocyte Proteinase 1; Cytolytic T Cell- and Natural Killer Cell-Specific Trypsin-Like Serine Protease; Granzyme 1; GZMA;

NCIt definition : Granzyme A (262 aa, 29 kDa) is encoded by the human GZMA gene. This protein plays a role in both proteolysis and apoptosis.;

Details

Origin ID

C121490;

UMLS CUI

C1313497;

Automatic exact mappings (from CISMeF team)
- Complement factor H [LOINC component]
- Complement factor h [OMIM gene]
- Factor H (substance) [SNOMED CT concept]
- Granzyme A (substance) [SNOMED CT concept]
- Granzyme a [OMIM gene]
- Heart failure [Bloc CIM-11]
- Hydrops fetalis [ORDO Disease]
- complement factor H [ORDO Gene]
- complement factor h [MeSH Descriptor]
- factor h [SNOMED Notion]
- granzyme A [MeSH concept]
- granzyme A [HGNC gene]
- granzymes [MeSH concept]
- granzymes [MeSH Descriptor]
OMIM relation
- Granzyme a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- GZMA protein, human [MeSH Supplementary Concept]
- GZMA protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- GZMA Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
- Natural Killer Cell [NCIt concept]
gene_product_has_associated_anatomy
- Secretory Granule [NCIt concept]
gene_product_has_biochemical_function
- Granzyme [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Granzyme A Mediated Apoptosis Pathway [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
- TSP-1 Induced Apoptosis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell-Mediated Cytotoxicity [NCIt concept]
- Hydrolysis [NCIt concept]
- Positive Regulation of Cytolytic Process [NCIt concept]
- Protein Cleavage [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients