Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1

Preferred Label : Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1;

NCIt synonyms : MALT Lymphoma-Associated Translocation Paracaspase; MALT1; Paracaspase-1; Paracaspase 1; Paracaspase; EC 3.4.22.-;

NCIt definition : Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (824 aa, 92kDa) is encoded by the MALT1 gene. This protein may play a role in NF-kappa-B activation.;

Details

Origin ID

C60673;

UMLS CUI

C1431888;

OMIM relation
- Malt1 paracaspase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- MALT1 protein, human [MeSH Supplementary Concept]
- MALT1 protein, human [MeSH concept]
- Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cysteine Peptidase Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- MALT1 Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- B Cell Receptor Signaling Pathway [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- Canonical NF-kappaB Signaling Pathway [NCIt concept]
- Shigellosis Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Immunity [NCIt concept]
- Protein Cleavage [NCIt concept]
- Proteolysis [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- MALT1 Inhibitor ABBV-525 [NCIt concept]
- MALT1 Inhibitor MPT-0118 [NCIt concept]
- MALT1 Inhibitor ONO-7018 [NCIt concept]
- MALT1 Inhibitor SGR-1505 [NCIt concept]
- Safimaltib [NCIt concept]

Keyword's position in hierarchy(ies) :

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