Antigen Peptide Transporter 2

Preferred Label : Antigen Peptide Transporter 2;

NCIt synonyms : Transporter 2, ABC (ATP Binding Cassette); TAP2; Peptide Transporter PSF2; Peptide Supply Factor 2; ATP-Binding Cassette, Sub-Family B, Member 3; Really Interesting New Gene 11 Protein; ABC Transporter, MHC 2; Peptide Transporter TAP2; ATP-Binding Cassette Sub-Family B Member 3; Peptide Transporter Involved In Antigen Processing 2; PSF-2; Transporter 2, ATP-Binding Cassette, Sub-Family B; ABC Transporter-MHC2; APT2;

NCIt definition : Antigen peptide transporter 2 (686 aa, 76 kDa) is encoded by the human TAP2 gene. This protein is involved in MHC class I protein folding and antigen presentation.;

Details

Origin ID

C21579;

UMLS CUI

C0165949;

OMIM relation
- Transporter, atp-binding cassette, major histocompatibility complex, 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- TAP2 protein, human [MeSH Supplementary Concept]
- TAP2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Multidrug Resistance Gene [NCIt concept]
- TAP2 Gene [NCIt concept]
- Translocase Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Antigen Presenting Cell [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- Permease [NCIt concept]
gene_product_has_chemical_classification
- Protein Complex Subunit [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- ABC Transporter Pathway [NCIt concept]
- Antigen Presentation Pathway [NCIt concept]
- Antigen Processing and Presentation Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Primary Immunodeficiency Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Processing [NCIt concept]
- Drug Efflux [NCIt concept]
- Immune Surveillance [NCIt concept]
- Ligand Binding [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Peptide Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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