Drug Efflux - CISMeF

Preferred Label : Drug Efflux;

NCIt definition : Transport of drugs out of a cell. A mechanism of drug resistance.;

Details

Origin ID

C19411;

UMLS CUI

C1512072;

Semantic type(s)
- Molecular Function [UMLS semantic type]
biological_process_has_associated_location
- Plasma Membrane [NCIt concept]
biological_process_has_initiator_chemical_or_drug
- Pharmacologic Substance [NCIt concept]
biological_process_has_result_biological_process
- Transmembrane Transport [NCIt concept]
biological_process_involves_gene_product
- ABC Transporter [NCIt concept]
- ATP-Binding Cassette Sub-Family A Member 2 [NCIt concept]
- ATP-Binding Cassette Sub-Family B Member 5 [NCIt concept]
- ATP-Binding Cassette Sub-Family B Member 6, Mitochondrial [NCIt concept]
- ATP-Binding Cassette Sub-Family C Member 8 [NCIt concept]
- ATP-Binding Cassette Sub-Family D Member 1 [NCIt concept]
- ATP-Binding Cassette Sub-Family F Member 2 [NCIt concept]
- ATP-Binding Cassette Sub-Family G Member 1 [NCIt concept]
- Antigen Peptide Transporter 1 [NCIt concept]
- Antigen Peptide Transporter 2 [NCIt concept]
- Bile Salt Export Pump [NCIt concept]
- Broad Substrate Specificity ATP-Binding Cassette Transporter ABCG2 [NCIt concept]
- Canalicular Multispecific Organic Anion Transporter 1 [NCIt concept]
- Canalicular Multispecific Organic Anion Transporter 2 [NCIt concept]
- Cholesterol Transporter ABCA5 [NCIt concept]
- Cystic Fibrosis Transmembrane Conductance Regulator [NCIt concept]
- Cytochrome P450 1A2 [NCIt concept]
- Deoxycytidine Kinase [NCIt concept]
- Glucosylceramide Transporter ABCA12 [NCIt concept]
- Lysosomal Cobalamin Transporter ABCD4 [NCIt concept]
- Multidrug Resistance Protein 1 [NCIt concept]
- Multidrug Resistance-Associated Protein 1 [NCIt concept]
- Multidrug Resistance-Associated Protein 4 [NCIt concept]
- Multidrug Resistance-Associated Protein 5 [NCIt concept]
- Multidrug Resistance-Associated Protein 6 [NCIt concept]
- Phosphatidylcholine Translocator ABCB4 [NCIt concept]
- Phospholipid-Transporting ATPase ABCA1 [NCIt concept]
- Phospholipid-Transporting ATPase ABCA3 [NCIt concept]
- Phospholipid-Transporting ATPase ABCA7 [NCIt concept]
biological_process_is_part_of_process
- Drug Metabolism [NCIt concept]
- Multidrug Resistance Process [NCIt concept]
process_involves_gene
- ABCB1 2 Allele [NCIt concept]
- ABCB1 Gene [NCIt concept]
- ABCB1 wt Allele [NCIt concept]
- ABCB4 Gene [NCIt concept]
- ABCB4 wt Allele [NCIt concept]
- ABCB5 Gene [NCIt concept]
- ABCB5 wt Allele [NCIt concept]
- ABCB6 Gene [NCIt concept]
- ABCB6 wt Allele [NCIt concept]
- ABCC1 Gene [NCIt concept]
- ABCC1 wt Allele [NCIt concept]
- ABCC3 Gene [NCIt concept]
- ABCC3 wt Allele [NCIt concept]
- ABCC6 Gene [NCIt concept]
- ABCC6 wt Allele [NCIt concept]
- ABCG2 Gene [NCIt concept]
- ABCG2 wt Allele [NCIt concept]
- DCK Gene [NCIt concept]
- DCK wt Allele [NCIt concept]
- IGFBP3 Gene [NCIt concept]
- IGFBP3 wt Allele [NCIt concept]
- Multidrug Resistance Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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