NCIt synonyms : ABCG2; ABC15; UAQTL1; EST157481; BCRP; BMDP; BCRP1; ABCP; MRX; MXR; MXR1; ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (Junior Blood Group) wt Allele; CD338; CDw338; GOUT1; ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 Gene; ATP-Binding Cassette, Subfamily G, Member 2 Gene; ATP-Binding Cassette Transporter, Placenta-Specific Gene;
NCIt definition : Human ABCG2 wild-type allele is located within 4q22 and is approximately 67 kb in
length. This allele, which encodesbroad substrate specificity ATP-binding cassette
transporter ABCG2 protein, plays a role in transmembrane transport and transcriptional
regulation. The allele is thought to play a role in cellular defense and aberrations
are thought to play a role in tumor multidrug resistance.;