ABCG2 wt Allele

Preferred Label : ABCG2 wt Allele;

NCIt synonyms : ABCG2; ABC15; UAQTL1; EST157481; BCRP; BMDP; BCRP1; ABCP; MRX; MXR; MXR1; ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (Junior Blood Group) wt Allele; CD338; CDw338; GOUT1; ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 Gene; ATP-Binding Cassette, Subfamily G, Member 2 Gene; ATP-Binding Cassette Transporter, Placenta-Specific Gene;

NCIt definition : Human ABCG2 wild-type allele is located within 4q22 and is approximately 67 kb in length. This allele, which encodesbroad substrate specificity ATP-binding cassette transporter ABCG2 protein, plays a role in transmembrane transport and transcriptional regulation. The allele is thought to play a role in cellular defense and aberrations are thought to play a role in tumor multidrug resistance.;

GenBank Accession Number : NM_004827;

Détails

Origin ID

C52276;

UMLS CUI

C1704927;

OMIM relation
- Atp-binding cassette, subfamily g, member 2 [OMIM gene]
See also inter- (CISMeF)
- Uric acid concentration, serum, quantitative trait locus 1 [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 4: 89436901-893700019 [NCIt concept]
gene_in_chromosomal_location
- 4q22 [NCIt concept]
gene_is_element_in_pathway
- ABC Transporter Pathway [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- HIF-2-Alpha Transcription Factor Pathway [NCIt concept]
gene_plays_role_in_process
- ATP Hydrolysis [NCIt concept]
- Drug Efflux [NCIt concept]
- Ligand Binding [NCIt concept]
- Multidrug Resistance Process [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]
- Tumorigenesis [NCIt concept]

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