Multidrug Resistance-Associated Protein 1

Preferred Label : Multidrug Resistance-Associated Protein 1;

NCIt synonyms : ABCC1; Multiple Drug Resistance-Associated Protein; MRP1 Protein; Leukotriene C(4) Tansporter; ATP-Binding Cassette, Sub-Family C, Member 1; Multiple Drug Resistance-Associated Protein 1; LTC4 Transporter; ATP-Binding Cassette Sub-Family C Member 1;

NCIt definition : Multidrug resistance-associated protein 1 (1531 aa, 172 kDa) is encoded by the human ABCC1 gene. This protein plays a role in the cellular export of both organic anions and xenobiotics.;

Details

Origin ID

C17682;

UMLS CUI

C1451297;

Automatic exact mappings (from CISMeF team)
- ATP binding cassette subfamily C member 1 [ORDO Gene]
- Atp-binding cassette, subfamily C, member 1 [OMIM gene]
- multidrug Resistance-Associated proteins [MeSH Descriptor]
Currated CISMeF NLP mapping
- multidrug resistance-associated protein 1 [MeSH concept]
- multidrug resistance-associated protein 1 [MeSH Supplementary Concept]
OMIM relation
- Atp-binding cassette, subfamily C, member 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ABCC1 protein, human [MeSH concept]
Validated automatic mappings to BTNT
- ABCC1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ABCC1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Multidrug Resistance Gene [NCIt concept]
- Translocase Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Lung [NCIt concept]
- Peripheral Blood Mononuclear Cell [NCIt concept]
- Testis [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- Permease [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- ABC Transporter Pathway [NCIt concept]
- Multi-Drug Resistance Factor Pathway [NCIt concept]
- Sphingosine 1-Phosphate Receptor 1 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Drug Efflux [NCIt concept]
- Ligand Binding [NCIt concept]
- Multidrug Resistance Process [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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