ABC Transporter

Preferred Label : ABC Transporter;

NCIt synonyms : ATP Binding Cassette Transporter; ABC Transport Protein; ABC Transporter Protein; ATP-Binding Cassette Transporter;

NCIt definition : A family of transmembrane proteins that usually function as dimers to hydrolyze ATP, which permits them to transport a wide variety of substrates across cellular membranes. These proteins consist of two distinct domains, a transmembrane domain and a nucleotide-binding domain. ATP binding is required for both dimerization and transporter activity.;

Details

Origin ID

C17750;

UMLS CUI

C0242738;

Currated CISMeF NLP mapping
- ATP-Binding cassette transporters [MeSH Descriptor]
- ATP-Binding cassette transporters [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ATP-Binding cassette transporters [MeSH concept]
- ATP-Binding cassette transporters [MeSH Descriptor]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Multidrug Resistance Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- Permease [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Drug Efflux [NCIt concept]
- Ligand Binding [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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