Canalicular Multispecific Organic Anion Transporter 2

Preferred Label : Canalicular Multispecific Organic Anion Transporter 2;

NCIt synonyms : MOAT-D; ABCC3; ATP-Binding Cassette Sub-Family C Member 3; Multi-Specific Organic Anion Transporter D; Multidrug Resistance-Associated Protein 3;

NCIt definition : Canalicular multispecific organic anion transporter 2 (1527 aa, 169 kDa) is encoded by the human ABCC3 gene. This protein is involved in both the transport and metabolism of bile.;

Details

Origin ID

C106023;

UMLS CUI

C1744264;

Automatic exact mappings (from CISMeF team)
- ATP binding cassette subfamily C member 3 [HGNC gene]
- Atp-binding cassette, subfamily C, member 3 [OMIM gene]
Currated CISMeF NLP mapping
- multidrug resistance-associated protein 3 [MeSH concept]
- multidrug resistance-associated protein 3 [MeSH Supplementary Concept]
OMIM relation
- Atp-binding cassette, subfamily C, member 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ABCC3 protein, human [MeSH concept]
- multidrug resistance-associated protein 3 [MeSH Supplementary Concept]
- multidrug resistance-associated protein 3 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ABCC3 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Multidrug Resistance Gene [NCIt concept]
- Translocase Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- Permease [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- ABC Transporter Pathway [NCIt concept]
- Multi-Drug Resistance Factor Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Bile Secretion Induction [NCIt concept]
- Drug Efflux [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Multidrug Resistance Process [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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