Glucosylceramide Transporter ABCA12

Preferred Label : Glucosylceramide Transporter ABCA12;

NCIt synonyms : ATP-Binding Cassette 12; ATP Binding Cassette Sub-Family A Member 12; ABCA12; ATP-Binding Cassette Transporter 12; EC 7.6.2.1; ATP Binding Cassette Subfamily A Member 12;

NCIt definition : Glucosylceramide transporter ABCA12 (2595 aa, 293 kDa) is encoded by the human ABCA12 gene. This protein is involved in both cellular cholesterol transport and the translocation of lipids, such as glucosylceramides, from the outer to the inner leaflet of the membranes of lamellar granules.;

NCI Metathesaurus CUI : CL372661;

Details

Origin ID

C191813;

UMLS CUI

C1258120;

OMIM relation
- Atp-binding cassette, subfamily a, member 12 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ABCA12 protein, human [MeSH Supplementary Concept]
- ABCA12 protein, human [MeSH concept]
gene_encodes_gene_product
- ABCA12 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Translocase Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Membrane of the Golgi Apparatus [NCIt concept]
- Secretory Vesicle [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- Permease [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- ABC Transporter Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cholesterol Homeostasis [NCIt concept]
- Drug Efflux [NCIt concept]
- Keratinocyte Differentiation [NCIt concept]
- Ligand Binding [NCIt concept]
- Lipid Transport [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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