Multidrug Resistance-Associated Protein 5

Preferred Label : Multidrug Resistance-Associated Protein 5;

NCIt synonyms : SMRP; ABCC5; MOAT-C; ATP-Binding Cassette Sub-Family C Member 5; Multi-Specific Organic Anion Transporter C; pABC11;

NCIt definition : Multidrug resistance-associated protein 5 (1437 aa, 161 kDa) is encoded by the human ABCC5 gene. This protein plays a role in the export of cyclic nucleotides.; Multidrug resistance-associated protein 5 (1437 aa, 161 kDa) is encoded by the human ABCC5 gene. This protein plays a role in the export of cyclic nucleotides.;

NCIt note : Multidrug resistance-associated protein 5 is associated with resistance to thiopurine anticancer drugs and the anti-HIV drug Adefovir.;

Details

Origin ID

C103951;

UMLS CUI

C1449272;

OMIM relation
- Atp-binding cassette, subfamily C, member 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ABCC5 protein, human [MeSH concept]
- ABCC5 protein, human [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- ABCC5 protein, human [MeSH concept]
- ABCC5 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ABCC5 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Multidrug Resistance Gene [NCIt concept]
- Translocase Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- Permease [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- ABC Transporter Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Drug Efflux [NCIt concept]
- Drug Transport Process [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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