HLA Class II Histocompatibility Antigen, DQ Beta 2 Chain

Preferred Label : HLA Class II Histocompatibility Antigen, DQ Beta 2 Chain;

NCIt synonyms : HLA-DQB2; MHC Class II Antigen DQB2; MHC Class II DQB2; HLA Class II Histocompatibility Antigen, DX Beta Chain; Major Histocompatibility Complex, Class II, DQ Alpha 2;

NCIt definition : HLA class II histocompatibility antigen, DQ beta 2 chain (268 aa, 30 kDa) is encoded by the human HLA-DQB2 gene. This protein plays a role in major histocompatibility complex-dependent antigen presentation.;

NCIt note : HLA class II histocompatibility antigen, DQ beta 2 chain (HLA-DQB2) forms a heterodimer with HLA-DQA2, but not with HLA-DQA1. Dimerization is required for efficient exit from the endoplasmic reticulum (ER). (UniProt);

Détails

Origin ID

C213628;

OMIM relation
- Major histocompatibility complex, class II, dq beta-2 [OMIM gene]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- HLA-DQB2 Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
- MHC Class II Gene [NCIt concept]
gene_product_expressed_in_tissue
- Antigen Presenting Cell [NCIt concept]
- CD4-Positive T-Lymphocyte [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- HLA Complex [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Allograft Rejection Pathway [NCIt concept]
- Antigen Processing and Presentation Pathway [NCIt concept]
- Asthma Pathway [NCIt concept]
- Autoimmune Thyroid Disease Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Graft-Versus-Host Disease Pathway [NCIt concept]
- Intestinal IgA Production Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
- Type I Diabetes Mellitus Pathway [NCIt concept]
- Viral Myocarditis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Presentation [NCIt concept]
- Immune System Process [NCIt concept]
- Immunoregulation [NCIt concept]
- Interferon Signaling Process [NCIt concept]
- T-Cell Activation [NCIt concept]

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