PDGFRL wt Allele

Preferred Label : PDGFRL wt Allele;

NCIt synonyms : Platelet-Derived Growth Factor Receptor-Like wt Allele; PDGRL; PRLTS;

NCIt definition : Human PDGFRL wild-type allele is located within 8p22-p21.3 and is approximately 66 kb in length. This allele, which encodes platelet-derived growth factor receptor-like protein, plays a putative role in the inhibition of cell growth and proliferation. Loss of PDGFRL gene function is associated with several types of cancer including colorectal cancers, hepatocellular carcinomas and non-small cell lung carcinomas.;

GenBank Accession Number : NM_006207;

Details

Origin ID

C54395;

UMLS CUI

C1709395;

OMIM relation
- Platelet-derived growth factor receptor-like [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Colorectal Carcinoma [NCIt concept]
- Hepatocellular Carcinoma [NCIt concept]
- Lung Non-Small Cell Carcinoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 8p22-p21.3 [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Tumor Suppression [NCIt concept]
- Tumorigenesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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