MeSH definition : A cell adhesion molecule that is expressed on the membranes of nearly all EPITHELIAL
CELLS, especially at the junctions between intestinal epithelial cells and intraepithelial
LYMPHOCYTES. It also is expressed on the surface of ADENOCARCINOMA and epithelial
tumor cells. It may function in the MUCOSA through homophilic interactions to provide
a barrier against infection. It also regulates the proliferation and differentiation
of EMBRYONIC STEM CELLS.;
A cell adhesion molecule that is expressed on the membranes of nearly all EPITHELIAL
CELLS, especially at the junctions between intestinal epithelial cells and intraepithelial
LYMPHOCYTES. It also is expressed on the surface of ADENOCARCINOMA and epithelial
tumor cells. It may function in the MUCOSA through homophilic interactions to provide
a barrier against infection. It also regulates the proliferation and differentiation
of EMBRYONIC STEM CELLS.