Proton-Coupled Folate Transporter

Preferred Label : Proton-Coupled Folate Transporter;

NCIt synonyms : Solute Carrier Family 46 Member 1; Heme Carrier Protein 1; Solute Carrier Family 46, Member 1;

NCIt definition : Proton-coupled folate transporter (459 aa, 50 kDa) is encoded by the human SLC46A1 gene. This protein plays a role in folate and antifolate transport across the plasma membrane, and heme transport in duodenal enterocytes.;

Details

Origin ID

C107468;

UMLS CUI

C1612271;

Automatic exact mappings (from CISMeF team)
- Proton-Coupled folate transporter [MeSH concept]
- Proton-Coupled folate transporter [MeSH Descriptor]
- Solute carrier family 46 (folate transporter), member 1 [OMIM gene]
- solute carrier family 46 member 1 [ORDO Gene]
- solute carrier family 46 member 1 [HGNC gene]
OMIM relation
- Solute carrier family 46 (folate transporter), member 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SLC46A1 protein, human [MeSH Supplementary Concept]
- SLC46A1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- SLC46A1 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Solute Carrier Family [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Folic Acid Metabolic Process [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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