Peroxisome Proliferator-Activated Receptor Gamma

Preferred Label : Peroxisome Proliferator-Activated Receptor Gamma;

NCIt synonyms : PPARG; PPARG2; PPAR Gamma; PPARG1; PPAR-gamma; Nuclear Receptor Subfamily 1 Group C Member 3; Peroxisome Proliferative Activated Receptor Gamma; Peroxisome Proliferator-Activated Receptor-Gamma; NR1C3;

NCIt definition : Peroxisome proliferator-activated receptor gamma (505 aa, 58 kDa) is encoded by the human PPARG gene. This protein plays a role in transcriptional regulation, lipid metabolism, cell differentiation, glucose homeostasis and apoptosis.;

Details

Origin ID

C34077;

UMLS CUI

C3887582;

Currated CISMeF NLP mapping
- PPAR gamma [MeSH concept]
- ppar gamma [MeSH Descriptor]
OMIM relation
- Peroxisome proliferator-activated receptor-gamma [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Nuclear Receptor Gene [NCIt concept]
- PPARG Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Efatutazone Dihydrochloride [NCIt concept]
- Phenyl Acetate [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Hormone Receptor [NCIt concept]
- Receptor [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Nuclear Hormone Receptor Superfamily [NCIt concept]
gene_product_has_structural_domain_or_motif
- Hormone Receptor DNA-Binding Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Calcineurin-Regulated NFAT-Dependent Transcription Pathway [NCIt concept]
- HDAC Class I Signaling Pathway [NCIt concept]
- Huntington's Disease Pathway [NCIt concept]
- Lipid Metabolism and Toxicity Pathway [NCIt concept]
- Metabolic Syndrome Pathway [NCIt concept]
- Noncanonical Wnt Signaling Pathway [NCIt concept]
- Obesity and Thermogenesis Pathway [NCIt concept]
- PPAR Pathway [NCIt concept]
- PPAR Signaling Pathway [NCIt concept]
- Papillary Thyroid Carcinoma Pathway [NCIt concept]
- Regulation of Retinoblastoma Protein Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Maturation [NCIt concept]
- Pattern Formation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Transcriptional Regulation [NCIt concept]
is_target
- Efatutazone Dihydrochloride [NCIt concept]
- Metformin Hydrochloride/Pioglitazone Hydrochloride Extended-Release Tablet [NCIt concept]
- PPAR Gamma Inhibitor FX-909 [NCIt concept]
- Rosiglitazone [NCIt concept]
- Rosiglitazone Maleate [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients