Receptor - CISMeF

Preferred Label : Receptor;

NCIt synonyms : Receptor Protein;

NCIt definition : A protein located on the cell surface, or in the cytoplasm, that binds to a specific signaling factor, such as a hormone, antigen, or neurotransmitter, causing a conformational and functional change in the receptor molecule. The ligand-bound receptor then alters its interaction with target molecules, which leads to changes in cellular physiology through modification of the activity of one or more signal transduction pathways.;

Alternative definition : NCI-GLOSS: A molecule inside or on the surface of a cell that binds to a specific substance and causes a specific physiologic effect in the cell.;

Codes from synonyms : CDR0000044958;

Details

Origin ID

C18106;

UMLS CUI

C0597357;

Automatic exact mappings (from CISMeF team)
- Receptor [UMLS semantic type]
- Receptors [OMIConto structure]
- Receptors [OMIConto index]
- receptor [IUPAC Term]
- receptors, aryl hydrocarbon [MeSH Descriptor]
- receptors, opioid, mu [MeSH Descriptor]
- receptors, proteinase-activated [MeSH Descriptor]
Biochemical function of gene products
- Cytoplasmic Receptor [NCIt concept]
- Fc Receptor [NCIt concept]
- Fc-Gamma Receptor [NCIt concept]
- Fc-Gamma Receptor II [NCIt concept]
- Fc-Gamma Receptor III [NCIt concept]
- Leukotriene Receptor Family [NCIt concept]
- Natural Cytotoxicity Receptor Family [NCIt concept]
- Notch Family [NCIt concept]
- Nuclear Receptor Subfamily 2 Group F Member 6 [NCIt concept]
- Nuclear Receptor Subfamily 4 Group A Member 3 [NCIt concept]
- Peroxisome Proliferator-Activated Receptor Gamma [NCIt concept]
- Platelet-Derived Growth Factor Receptor [NCIt concept]
- Prolactin Receptor [NCIt concept]
- Purinergic P1 Receptor [NCIt concept]
- Purinergic Receptor [NCIt concept]
- Retinoic Acid Receptor Beta [NCIt concept]
- Thyroid Hormone Receptor [NCIt concept]
- Thyroid Hormone Receptor Alpha [NCIt concept]
- Thyroid Hormone Receptor Beta [NCIt concept]
False automatic mappings
- Receptor (substance) [SNOMED CT concept]
- receptor [IUPAC Term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Receptor (substance) [SNOMED CT concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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