Fc-Gamma Receptor

Preferred Label : Fc-Gamma Receptor;

NCIt synonyms : Fc Gamma Receptor; FCGR; Fc-Gamma R; Fc Gamma R; Fc GammaR; Fc-GammaR;

NCIt definition : Receptors belonging to the immunoglobulin superfamily that bind to the Fc portion of IgG molecules and play a role in the phagocytosis of opsonized bacteria.;

NCIt note : There are 5 receptors in this family, Fc gamma RI (CD64), Fc gamma RIIA (CD32), Fc gamma RIIB (CD32), Fc gamma RIIIA (CD16a), Fc gamma RIIIB;

Details

Origin ID

C104675;

UMLS CUI

C0123263;

Biochemical function of gene products
- High Affinity Immunoglobulin Gamma Fc Receptor I [NCIt concept]
Currated CISMeF NLP mapping
- receptors, IgG [MeSH Descriptor]
- receptors, IgG [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- receptors, IgG [MeSH concept]
- receptors, IgG [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Immunoglobulin Family Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Immunoglobulin Binding Protein [NCIt concept]
- Receptor [NCIt concept]
gene_product_has_chemical_classification
- Cell Surface Receptor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_plays_role_in_biological_process
- Antimicrobial Effect [NCIt concept]
- Cell-Mediated Cytotoxicity [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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